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Peripheral Nerve Blocks Have Significant Benefit in Older Patients undergoing Abdominal Procedures

February 18, 2025

Zhang Z, Li C, Xu ZZ, Ma JH, Wang DX. Effects of Peripheral Nerve Block on Perioperative Recovery Following Major Thoracic and Abdominal Surgery: A Retrospective Cohort Study with Propensity-score Matching. Ann Surg. 2025; in press.

This retrospective cohort study (n = 1,915) compared patients >65 years of age scheduled to undergo thoracic or abdominal surgical procedures who received peripheral nerve blocks (PNB) combined with general anesthesia (n = 1,316) with patients who received general anesthesia alone (n = 599).

Patients were matched using propensity scores. Nerve blocks administered included thoracic paravertebral, transversus abdominis plane, erector spinae plane, or quadratus lumborum block.

The data analysis showed that patients who received PNB had significantly fewer major in-hospital complications and a shorter length of hospital stay. The PNB group also required smaller doses of supplemental analgesia.

The authors concluded that PNB had significant benefit in older patients undergoing major thoracic or abdominal procedures.

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